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Herbert Kim Lyerly, MD

George Barth Geller Distinguished Professor of Immunology
Campus Mail: 203 Research Drive, Rm 433B, Box 2606, Durham, NC 27710
Phone: (919) 681-8350

Education and Training

  • M.D., University of California, Los Angeles, 1983

Selected Grants and Awards

Selected Publications

Morse, M. A., J. J. Vredenburgh, and H. K. Lyerly. “A comparative study of the generation of dendritic cells from mobilized peripheral blood progenitor cells of patients undergoing high-dose chemotherapy.” J Hematother Stem Cell Res 8, no. 6 (December 1999): 577–84.

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Nair, S. K., S. Hull, D. Coleman, E. Gilboa, H. K. Lyerly, and M. A. Morse. “Induction of carcinoembryonic antigen (CEA)-specific cytotoxic T-lymphocyte responses in vitro using autologous dendritic cells loaded with CEA peptide or CEA RNA in patients with metastatic malignancies expressing CEA.” Int J Cancer 82, no. 1 (July 2, 1999): 121–24.<121::aid-ijc20>;2-x.

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Morse, M. A., Y. Deng, D. Coleman, S. Hull, E. Kitrell-Fisher, S. Nair, J. Schlom, M. E. Ryback, and H. K. Lyerly. “A Phase I study of active immunotherapy with carcinoembryonic antigen peptide (CAP-1)-pulsed, autologous human cultured dendritic cells in patients with metastatic malignancies expressing carcinoembryonic antigen.” Clin Cancer Res 5, no. 6 (June 1999): 1331–38.


Morse, M. A., R. E. Coleman, G. Akabani, N. Niehaus, D. Coleman, and H. K. Lyerly. “Migration of human dendritic cells after injection in patients with metastatic malignancies.” Cancer Res 59, no. 1 (January 1, 1999): 56–58.


Morse, M. A., H. K. Lyerly, E. Gilboa, E. Thomas, and S. K. Nair. “Optimization of the sequence of antigen loading and CD40-ligand-induced maturation of dendritic cells.” Cancer Res 58, no. 14 (July 15, 1998): 2965–68.


Morse, M. A., L. J. Zhou, T. F. Tedder, H. K. Lyerly, and C. Smith. “Generation of dendritic cells in vitro from peripheral blood mononuclear cells with granulocyte-macrophage-colony-stimulating factor, interleukin-4, and tumor necrosis factor-alpha for use in cancer immunotherapy.” Ann Surg 226, no. 1 (July 1997): 6–16.

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