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Herbert Kim Lyerly, MD

George Barth Geller Professor
Campus Mail: 203 Research Drive, Rm 433B, Box 2606, Durham, NC 27710
Phone: (919) 681-8350

Education and Training

  • M.D., University of California at Los Angeles, 1983

Selected Grants and Awards

Selected Publications

Boczkowski, D, Nair, SK, Nam, JH, Lyerly, HK, and Gilboa, E. "Induction of tumor immunity and cytotoxic T lymphocyte responses using dendritic cells transfected with messenger RNA amplified from tumor cells." Cancer Res 60, no. 4 (February 15, 2000): 1028-1034.


Morse, MA, Vredenburgh, JJ, and Lyerly, HK. "A comparative study of the generation of dendritic cells from mobilized peripheral blood progenitor cells of patients undergoing high-dose chemotherapy." J Hematother Stem Cell Res 8, no. 6 (December 1999): 577-584.

Full Text

Morse, MA, Lyerly, HK, and Li, Y. "The role of IL-13 in the generation of dendritic cells in vitro." J Immunother 22, no. 6 (November 1999): 506-513.


Nair, SK, Hull, S, Coleman, D, Gilboa, E, Lyerly, HK, and Morse, MA. "Induction of carcinoembryonic antigen (CEA)-specific cytotoxic T-lymphocyte responses in vitro using autologous dendritic cells loaded with CEA peptide or CEA RNA in patients with metastatic malignancies expressing CEA." Int J Cancer 82, no. 1 (July 2, 1999): 121-124.


Morse, MA, Deng, Y, Coleman, D, Hull, S, Kitrell-Fisher, E, Nair, S, Schlom, J, Ryback, ME, and Lyerly, HK. "A Phase I study of active immunotherapy with carcinoembryonic antigen peptide (CAP-1)-pulsed, autologous human cultured dendritic cells in patients with metastatic malignancies expressing carcinoembryonic antigen." Clin Cancer Res 5, no. 6 (June 1999): 1331-1338.


Morse, MA, Coleman, RE, Akabani, G, Niehaus, N, Coleman, D, and Lyerly, HK. "Migration of human dendritic cells after injection in patients with metastatic malignancies." Cancer Res 59, no. 1 (January 1, 1999): 56-58.


Morse, MA, Lyerly, HK, Gilboa, E, Thomas, E, and Nair, SK. "Optimization of the sequence of antigen loading and CD40-ligand-induced maturation of dendritic cells." Cancer Res 58, no. 14 (July 15, 1998): 2965-2968.


Morse, MA, Zhou, LJ, Tedder, TF, Lyerly, HK, and Smith, C. "Generation of dendritic cells in vitro from peripheral blood mononuclear cells with granulocyte-macrophage-colony-stimulating factor, interleukin-4, and tumor necrosis factor-alpha for use in cancer immunotherapy." Ann Surg 226, no. 1 (July 1997): 6-16.